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Search Results for " bone marrow serine protease "

Targets Recommended: Others

2

抑制剂 & 化合物

5

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T8645	PF-06446846	Others	Others
	PF-06446846 是口服有活性的 PCSK9抑制剂。它能够在密码子区域附近阻断 80S ribosome，选择性地直接抑制 PCSK9 的翻译。
T16491	PF-06446846 hydrochloride	Others	Others
	PF-06446846 hydrochloride 是一种口服活性高、高选择性PCSK9(前蛋白转化酶枯草杆菌蛋白酶/kexin 9 型)翻译抑制剂。它通过在密码子34附近诱导核糖体暂停来抑制PCSK9。

化合物

Cat.No: T8645

Target: Others

PF-06446846 hydrochloride

Cat.No: T16491

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01773	ELANE Protein, Human, Recombinant (GST) Neutrophil elastase,ELA2,Medullasin,Elastase-2,ELANE,Bon...	Human	E. coli
	Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane protein A (ompA) in E.coli and K.pneumoniae. ELANE Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 52.6 kDa and the accession number is P08246.
TMPJ-01253	Serpin A3N Protein, Mouse, Recombinant (His) Serpina3n,Serine protease inhibitor A3N,Sp...	Mouse	HEK293 Cells
	Serine protease inhibitor A3N(Serpin A3N) is a serine protease inhibitor that is structurally related to α1 antichymotrypsin encoded by the SERPINA3 gene. Serpin A3N is highly expressed in brain, testis, lung, thymus, and spleen. It is expressed with low levels in bone marrow, kidney and skeletal muscle. Serpin A3N secreted by Sertoli cells may regulate the activity of locally produced Granzyme B. Granzyme B inhibition by Serpin A3N may therefore regulate Granzyme Bmediated killing by cytotoxic ...
TMPY-01589	Serpin B10 Protein, Mouse, Recombinant (His) Serpinb10-ps,serpin peptidase inhibitor, clade B (ovalbumin)...	Mouse	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhi...
TMPJ-01282	Serpin B12 Protein, Human, Recombinant (His) SERPINB12,Serine Protease Inhibitor-clade ...	Human	HEK293 Cells
	Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Serpin B12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestine. Serpins are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysi...
TMPY-01718	Serpin B12 Protein, Mouse, Recombinant (His) 2300003F07Rik,4833409F13Rik,serpin peptidase inhibitor, clad...	Mouse	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Mouse SerpinB12 is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. It ...

重组蛋白

ELANE Protein, Human, Recombinant (GST)

Cat.No: TMPH-01773

Species: Human

Expression System: E. coli

Serpin A3N Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01253

Species: Mouse

Expression System: HEK293 Cells

Serpin B10 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01589

Species: Mouse

Expression System: Baculovirus Insect Cells

Serpin B12 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01282

Species: Human

Expression System: HEK293 Cells

Serpin B12 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01718

Species: Mouse

Expression System: Baculovirus Insect Cells

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